Home World News Polytoxic Nephrology: Generalized Cell Death

Polytoxic Nephrology: Generalized Cell Death

0
Polytoxic Nephrology: Generalized Cell Death

Two people have died from food poisoning at Taiwan’s Baolin Tea House. The Ministry of Health and Welfare announced on Thursday night that for the first time in Taiwan, the toxic substance “rice zymocyanin” was found in the dead.Nephrologist Wang Jili is hereFacebookSaid that rice fermentation is a mitochondrial toxin. If the Earth is compared to the human body and the country is compared to cells, mitochondria are the power plants of the country. The role of zymozoic acid is to launch an indiscriminate attack on all power plants on the planet, which is equivalent to putting the world directly into blackout.

Wang Jelli said that cells in the human body cannot breathe and produce energy, so complete cell death occurs. The most familiar mitochondrial toxin is cyanide.

He said that at present it is known that this toxin is produced by only one type of bacteria. The name of the bacteria is Burkholderia gladioli pathovar cocovanense (B. cocovanense). This is not a common human pathogenic bacteria. “This means that it is bacteria. Will not invade the human body and will not cause disease”, but bacteria are widely present in the environment.

Regarding cases caused by rice fermentation acid in the past, Wang Jili said that the earliest cases wereIndonesia, from a food called tempeh bongkrek, which is made using coconut by-products and using Rhizopus oligosporum mold in the fermentation process. It was first reported in 1895, exclusively on the island of Java. Major incidents occurred between 1951 and 1975, affecting 7,216 people and killing 850. After 1988, although the production of tempeh bongkrek was officially banned in Indonesia, there were still occasional incidents of poisoning. The overall mortality rate averages 60%.

In later reports in China, Wang Jelli said it comes mainly from fermented corn products and is used to make bread, noodles and.steamed dumplings, In the south, Tangtang cake and half white fungus which may be contaminated with soil are also related to the incidence of poisoning. From 1953 to 1974, 665 people were affected in Heilongjiang province and 288 died. From 1990 to 2006, 121 people were reported affected and 76 deaths were reported in Guangxi.

Wang Jieli said that in 2015, the first poisoning incident in a non-Asian region was reported in Mozambique, Africa, which affected people who drank homemade fermented corn flour beverage, resulting in 75 deaths. .

Wang Jieli said that specific favorable conditions for bacteria to produce toxins include temperature. They are more active in hot environments. The ideal temperature range is 22 to 30 °C, which is similar to the production conditions of tempeh. The second is the pH value. A more neutral to slightly alkaline pH value (6.5 to 8.0) is favorable for the production of toxins. The third is NaCl concentration. Salt concentrations less than 1.5 to 2% are more suitable for BA production. The fourth is the type of fatty acid. When the concentration of fatty acids is between 20 to 50%, especially glycerin, oleic acid, lauric acid, myristic acid and palmitic acid, it is conducive to the production of toxins. As long as conditions are suitable, 2 to 4 mg/gram of toxin can be produced in 2 days of culture.

There are still few reports on the toxicokinetic properties of this toxin, but Wang Jiely said that because it is highly fat soluble, it is estimated that its distribution volume in the human body is large, “and it is usually not treated by hemodialysis or such.” Represents treatments plasma exchange., the effect of removing toxins is very poor.

Taiwan (TagstoTranslate) Indonesia (T) Dumplings (T) Facebook